Projects

CANCER RESEARCH UK - United Kingdom 

Project overview (since 2010-01-01):

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Start dateProjectacronymrolefundingpartners
2017-01-01Translational Research Network in Prostate Cancer TransPotparticipant2.629.31618
2015-08-01Investigating eukaryotic replisome dynamics at the single molecule level SMI REPparticipant195.4552
2015-06-01Structural and biochemical characterization of pre-recombination complexes BRCA2Interactcoordinator183.4551
2015-06-01Systematic investigation of the functional coupling between transcriptional and post-transcriptional regulatory interactions underlying tissue-specific 3'UTRs variability. NeuroUTRcoordinator183.4551
2015-05-01Development and immunological control of dendritic cell cancer DC cancercoordinator183.4551
2015-03-01The interplay between innate immunity and RNA interference in mammals RNAi vs IFNparticipant309.2352
2014-09-01Anatomy and dynamics of the human replisome ANDYHREPcoordinator221.6061
2014-06-01Tumour Heterogeneity and Somatic Evolution of Unstable cancer genomes THESEUSparticipant1.999.9412
2014-04-01Structural and biochemical characterization of the BRCA2 breast cancer tumour suppressor BRCA2COMPLEXEScoordinator231.2831
2014-04-01Role of nuclear architecture in cancer development ACTINNUCLSHAPECANCERcoordinator231.2831
2014-01-01Asymmetrical B cell division: origin and functional significance ASYMMETRY IN B CELLScoordinator221.6061
2013-10-01The impact of chromosomal instability on health: Molecular causes and consequences of aneuploidy PLOIDYNETparticipant3.017.79011
2013-07-01Single cell level intravital imaging of response, tolerance, and resistance to targeted therapies IMAGEMELTHERAPYLRIcoordinator231.2831
2013-07-01Design Principles of Microtubule Cytoskeleton Architectures during Cell Division SPINDLEDESIGNparticipant2.497.1151
2013-06-01In vitro reconstitution of the replication machinery on a chromatin template DNA REPLICATIONcoordinator221.6061
2013-05-01The dendritic cell receptor DNGR-1: Modulation of endosomal dynamics upon recognition of necrotic cells DNGR-1 IN DCScoordinator221.6061
2013-05-01Mechanism of Holliday junction dissolution by the Bloom’s Syndrome complex BLMCOMPLEXcoordinator221.6061
2013-05-01Targeting RAS oncogene addiction RASTARGETparticipant2.496.2211
2013-04-01Regulation of the Hippo tissue growth pathway by nutrient sensing mechanisms in Drosophila melanogaster HIPPOGAILITEcoordinator221.6061
2013-04-01Functional analysis of SCOC and FEZ proteins in autophagy using mammalian cell models and zebrafish SCOC AND FEZcoordinator221.6061
2012-10-01Generation of a new class of antiretrovirals targeting HIV-cellular cofactors interactions HIVINNOVparticipant6.000.0006
2012-07-31Function of centromeres during meiotic bouquet stage and protein composition of telomeres meiotic centromerescoordinator182.1031
2012-07-01Identification of important regulators of metastasis in pancreatic cancer Cancer metastasiscoordinator200.3721
2012-04-15Gene Discovery in Melanoma Progression and Therapeutic Resistance Melanoma Genesparticipant209.5932
2012-02-01ATMINistrating ATM signalling: exploring the significance of ATM regulation by ATMIN ATMINDDRparticipant1.499.8812
2011-10-01MAL: an actin-regulated SRF transcriptional coactivator ACTINONSRFparticipant1.889.9952
2011-09-01Cross-species characterisation of CD8alpha+ dendritic cells and their role in immune regulation DCSUBSETparticipant2.499.9982
2011-07-01RGS1 in intestinal T cell trafficking and responsiveness RITTARcoordinator209.0931
2011-05-01Transcription and the maintenance of genome integrity TRANSINTEGparticipant1.950.0002
2011-05-01Regulating recombination in mitotic and meiotic cells RECMITMEIparticipant2.379.1042
2011-05-01Imaging influenza nucleic acid recognition by RIG-I in living cells RIG‐I Live Imagingcoordinator200.0501
2011-03-01“The role of ALC1, a novel ATP-dependent chromatin remodelling protein, in transcriptional regulation, tumorigenesis and neurodegeneration” chromALC1hcccoordinator172.7411
2011-02-01Targeting the tumour microenvironment to improve pancreatic cancer prognosis EPC-TM-Netparticipant3.000.00017
2011-02-01The role of Rab7 in axonal retrograde transport and human pathologies retrograde transportcoordinator173.2411
2011-01-01New approaches for the targeted therapy of Non-Small Cell Lung Cancer LUNGTARGETparticipant2.997.33210
2011-01-01ERA-NET on Translational Cancer Research TRANSCANparticipant1.999.95629
2011-01-01Predicting individual response and resistance to VEGFR/mTOR pathway therapeutic intervention using biomarkers discovered through tumour functional genomics PREDICTparticipant5.841.00914
2011-01-01Investigation of a dependency of RAS-driven cancers on matrix metalloproteinase-7 RAS and MMP7coordinator172.7411
2010-10-01Epigenetics towards systems biology EPIGENESYSparticipant11.995.02428
2010-08-01Molecular control of vascular remodelling: A role for Wnt signalling WNT VASCULAR REMODELcoordinator173.2411
2010-07-01The role of hypoxia-inducible factors in human haematopoietic stem cell biology and leukaemogenesis HSCs and HIFcoordinator172.7411
2010-07-01Investigating the Functional Implications of MICA Polymorphisms IFIMAPcoordinator172.2411
2010-07-01Breast Cancer Somatic Genetics Study BASISparticipant10.499.99915
2010-06-01Telomere function in meiosis Telomeres in meiosisparticipant1.451.9431
2010-06-01Defects in DNA strand break repair and links to inheritable disease DNArepairparticipant2.449.0912
2010-05-01The Initiation of Eukaryotic DNA Replication: Mechanism, Regulation and Role in Genome Stability EUKDNAREPparticipant2.449.9992
2010-04-01A molecular view of chromosome condensation ChromoCondparticipant2.076.1261
2010-03-31The role of JNK/c-Jun pathway in axonal damage and neuronal regeneration JNKNeuroregcoordinator171.8681
2010-03-31Functional characterization of indirect dendritic cell activation and its impact on adaptive immunity DC-ACTIVATIONcoordinator181.3511
2010-03-01New imaging methods for detecting treatment response in lymphoma IMAGING LYMPHOMAcoordinator172.7411
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